2-Amino-4-nitrophenol 2-氨基-4-硝基苯酚

规格: 98%
CAS: 99-57-0
产品编号: H99615
MDL: MFCD00007695
品牌: INFI
Chemical Name2-Amino-4-Nitrophenol
CAS Number99-57-0
Synonym 1-Amino-2-hydroxy-5-nitrobenzene 1-Hydroxy-2-amino-4-nitrobenzene 1-Nitro-3-amino-4-hydroxybenzene 1-amino-2-hydroxy-5-nitrobenzene 1-hydroxy-2-amino-4-nitrobenzene 2-AMINO-4-NITROPHENOL 2-Amino-4-nitro phenol 2-Amino-4-nitrofenol 2-Amino-4-nitrophenol 2-HYDROXY-5-NITROANILINE 2-Hydroxy-5-nitroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID3613389
EC Number202-767-9
Beilstein Registry Number13(2)192
MDL NumberMFCD00007695
Reaxys-RN776533
Chemical Name Translation2-氨基-4-硝基苯酚
Wiswesser Line NotationZR BQ ENW
LabNetwork Molecule IDLN00008082
InChIInChI=1S/C6H6N2O3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H,7H2
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 64375 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Endocrine - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-339,1988

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 246 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 2,657,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Skin and Appendages - hair
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,607,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 143 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GPOLA4 Genetica Polonica.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)
   V.1-    1960-  Volume(issue)/page/year: 26,109,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 25(8),50,1981

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   MDMIAZ Medycyna Doswiadczalna i Mikrobiologia.  For English translation, see
   EXMMAV.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)  V.1-    1949-
   Volume(issue)/page/year: 31,11,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 ug/plate
REFERENCE :
   CMMUAO Chemical Mutagens.  Principles and Methods for Their Detection.
   (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  V.1-    1971-
   Volume(issue)/page/year: 8,151,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 72,2423,1975

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 5 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-339,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 249 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-339,1988

WGK Germany2
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H303 May be harmfully swallowed 吞食可能有害
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
    Hazard Codes Xn Xi Xi,Xn
    RTECSSJ6300000
    Precautionary statements
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
    • P332+P313
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P302+P350
    • P337+P313
    • P302+P352+P332+P313+P362+P364
    • P305+
      Signal word Warning
      Safety Statements
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
      • S24 Avoid contact with skin 避免皮肤接触;
      • S37 Wear suitable gloves 戴适当手套;
      • S36 Wear suitable protective clothing 穿戴适当的防护服;
        Risk Statements
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
        • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
        • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
        • R36 Irritating to eyes 刺激眼睛
        • R22 Harmful if swallowed 吞咽有害
          UN Number 2811
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 作染料和医药的中间体。用于酸性媒性棕RH;中性黑BL、BRL、BGL等
        • {uni_hamburg} Short: IV/4
        • {uni_hamburg} Short: EINECS
        • {ALD} Beilstein:13(2)192
        • {TRC} Burnett, C. et al.: J. Toxicol. Env. Health, 2, 657 (1977); Burnett, C. et al.: Intt. J. Toxicol., 28, 217S (2009);
        • 99-57-0 H99615 2-Amino-4-nitrophenol
2-氨基-4-硝基苯酚

          化学属性

          Mol. FormulaC6H6N2O3
          Mol. Weight154
          Melting Point144.0 to 148.0 deg-C
          Density1.511
          TSCAYes
          Flash Point100 ºC
          Solubility略溶于水
          RedoxOxidation

          *以上化合物性质及应用等信息仅供参考