Ellagic acid hydrate 鞣花酸

规格: 97%
CAS: 476-66-4
产品编号: H96359
MDL: MFCD00006914
品牌: INFI
Chemical NameEllagic acid
Synonym 2,3,7,8-Tetrahydroxy(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione 4,3-cde][1]benzopyran-5,10-dione,2,3,7,8-tetrahydroxy-[1]-Benzopyrano[5 4,4',5,5',6,6'-HEXAHYDROXYDIPHENIC ACID 2,6,2',6'-DILACTONE 4,4',5,5',6,6'-HEXAHYDROXYDIPHENIC ACID DILACTONE 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone AKOS NCG1-0028 Acid, Benzoaric Acid, Ellagic Benzoaric Acid Benzoaric acid Elagostasine Ellagic Acid Lagistase alizarineyellow c.i.75270 lagistase 二缩双(三羟基苯甲酸) 倍原 土耳其鞣酸 棓原;逆没食子酸,二缩双(三羟基甲酸); 2,3,7,8-四羟基-[1]-苯并吡喃并[5,4,3-CDE][1]苯并吡喃-5,10-二酮 逆没食子酸 鞣花酸二水化合物 鞣花酸水合物
MDL NumberMFCD00006914
Beilstein Registry Number47549
CAS Number476-66-4
EC Number207-508-3
PubChem Substance ID5281855
Chemical Name Translation柔花酸
Merck Number3547
Reaxys-RN47549
LabNetwork Molecule IDLN00196863
InChIInChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1208 mg/kg
SEX/DURATION            : female 16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
   Reproductive - Specific Developmental Abnormalities - blood and lymphatic
   systems (including spleen and marrow)
REFERENCE :
   AMBPBZ Acta Pathologica et Microbiologica Scandinavica, Section A:
   Pathology.  (Copenhagen, Denmark) V.78-89, 1970-81.  For publisher
   information, see ACPADQ.  Volume(issue)/page/year: 79,487,1971

RTECSDJ2620000
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
    Hazard statements
    • H315 Causes skin irritation 会刺激皮肤
    • H319 Causes serious eye irritation 严重刺激眼睛
    • H335 May cause respiratory irritation 可能导致呼吸道刺激
      WGK Germany1
      Signal word Warning
      Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
      Hazard Codes Xi
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
        Risk Statements
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
          Storage condition 充氩密封避光保存。 对光和空气敏感，充氩密封避光保存。
          UN Number
          Packing Group
        • 常见于多酚植物。谷胱甘肽S-转移酶的抑制剂，常用于检测血浆中XIIa 因子；抗氧化剂；DNA双链的保护剂。
        • {MCE} [2]. Rizk HA, et al. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. J Biochem Mol Toxicol. 2017 Dec;31(12).
        • {MCE} [3]. Ahire V, et al. Ellagic Acid Enhances Apoptotic Sensitivity of Breast Cancer Cells to γ-Radiation. Nutr Cancer. 2017 Aug-Sep;69(6):904-910.
        • {ALD} Merck: 14,3547
        • {ALD} Merck: 14,3547
        • Beilstein:19,261
        • {MCE} [1]. Cozza G, et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6.
        • {MCE} [1]. Cozza G, et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6.
        • {MCE} [2]. Rizk HA, et al. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. J Biochem Mol Toxicol. 2017 Dec;31(12).
        • {MCE} [3]. Ahire V, et al. Ellagic Acid E
          • 476-66-4 H96359 Ellagic acid hydrate 鞣花酸

          化学属性

          Mol. FormulaC14H6O8
          Mol. Weight302
          Melting Point300
          Density1.667
          Solubility<0.1 G/100 ML AT 21 ºC
          Appearance powder
          Stability对空气敏感，对光敏感
          Boiling Point

          *以上化合物性质及应用等信息仅供参考