1,3-Dichloro-2-propanol 1,3-二氯丙醇

规格: 98%
CAS: 96-23-1
产品编号: H86474
MDL: MFCD00000951
品牌: INFI
Chemical Name1,3-Dichloro-2-propanol
MDL NumberMFCD00000951
CAS Number96-23-1
Synonym 1 1,3-DICHLORO-2-PROPANOL 1,3-dichloroisopropanol 1,3-二氯-2-丙醇 1,3-二氯丙醇 1,3-二氯丙醇, 98+% 1,3-二氯代甘油 1-二乙基氨基-2-丁炔, 98+% 3-二氯-2-丙醇 A,A'-DICHLORO ALPHA,GAMMA-GLYCERINDICHLOROHYDRIN Dichlorohydrin Enodrin GLYCEROL CHLOROHYDRIN GLYCEROL-ALPHA GLYCEROL-ALPHA,GAMMA-DICHLOROHYDRIN Glycerol alpha,gamma-dichlorohydrin Glycerol-alpha,gamma-dichlorohydrin SYM-GLYCEROL DICHLOROHYDRIN U 25,354 alpha-Dichlorohydrin dichloropropanol sym-Dichloroisopropyl alcohol sym-Glycerol dichlorohydrin Β,Βˊ-二氯代异丙醇 α,α'-Dichlorohydrin, Glycerol-α,γ-dichlorohydrin 二氯丙醇-(2) 二氯异丙醇 二氯甘油
PubChem Substance ID7289
EC Number202-491-9
Beilstein Registry Number1732063
Merck Number3074
Chemical Name Translation1,3-二氯-2-丙醇
Reaxys-RN1732063
Wiswesser Line NotationG1YQ1G
LabNetwork Molecule IDLN00189337
InChIInChI=1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4550 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0539378

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 125 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 69,203,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 800 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 2,59,1980

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 92,427,1982

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 30 umol/tube
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   80,73,1991

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 250 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 9,401,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   200,785,1978

WGK Germany3
Hazard statements
  • H350 May cause cancer 可能致癌
  • H312 Harmful in contact with skin 皮肤接触有害
  • H301 Toxic if swallowed 吞食有毒
  • H227 Combustible liquid 可燃液体
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSUB1400000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
    • P301+P310
    • P302+P350
    • P304+P340+P310
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P308+P311
    • P308+P313
    • P332+P313
    • P337+P313
    • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
    • P403+P233
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Packing GroupII
      UN Number 2750 UN 2750 6.1/PG 2 UN2733 UN2750
      Risk Statements
      • R10 Flammable 易燃
      • R11 Highly flammable 非常易燃
      • R21 Harmful in contact with skin 与皮肤接触有害
      • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
      • R25 Toxic if swallowed 吞咽有毒
      • R34 Causes burns 会导致灼伤
      • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
      • R45 May cause cancer 可能致癌
        Safety Statements
        • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
        • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
          Hazard Codes 6.1 T T,F
          Hazard Class6.1
          Storage condition 2-8°C
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 用作乙酸纤维、乙基纤维的溶剂。也是环氧树脂、离子交换树脂、环氧氯丙烷的中间体
        • {ALD} Merck: 14,3074
        • Beilstein:1,364
        • {ALD} Merck: 14,3074
        • 96-23-1 H86474 1,3-Dichloro-2-propanol
1,3-二氯丙醇

          化学属性

          Mol. FormulaC3H6Cl2O
          Mol. Weight129
          Refractive index1.4820 to 1.4850
          Boiling Point172-176
          Density1.351
          Melting Point-4
          Flash Point74°C(lit.)
          TSCAYes
          Solubilitysoluble. >=10 g/100 mL at 23 °C

          *以上化合物性质及应用等信息仅供参考