6-Hydroxypurine 6-羟基嘌呤

规格: 99.5%
CAS: 68-94-0
产品编号: H80693
MDL: MFCD00005725
品牌: INFI
Chemical NameHypoxanthine
CAS Number68-94-0
Synonym Hypoxanthine {LY} Hypoxanthine {} {LY} Hypoxanthine {} {} {LY} Hypoxanthine {} {} {} {LY} Hypoxanthine {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hypoxanthine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number200-697-3
Beilstein Registry Number5811
MDL NumberMFCD00005725
PubChem Substance ID135398638
Merck Number4869
Reaxys-RN608599
Chemical Name Translation次黄嘌呤
Wiswesser Line NotationT56 BN DM FVM INJ
LabNetwork Molecule IDLN00195829
InChIInChI=1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
Canonical SMILESO=C1NC=NC2=C1N=CN2
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 600 mg/kg
SEX/DURATION            : female 13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 22,201,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1 gm/kg
SEX/DURATION            : female 13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 22,201,1972

Signal word Warning
WGK Germany3
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
    Risk Statements
    • R22 Harmful if swallowed 吞咽有害
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P312
      • P302+P352
      • P305+P351+P338
        RTECSUP0791000
        Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
        Hazard Codes Xn
        Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
      • 生化试剂，制备生物培养基。
      • {TRC} Jansen, R., et al.: Clin. Biochem., 38, 362 (2005),
      • {ALD} Merck: 14,4869
      • {ALD} Merck: 14,4869
      • Beilstein:26,416
      • {uni_hamburg} Short: III/20a
      • {uni_hamburg} Short: III/31a
      • {MCE} [1]. Saugstad OD, et al. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50.
        • 68-94-0 H80693 6-Hydroxypurine 6-羟基嘌呤

        化学属性

        Mol. FormulaC5H4N4O
        Mol. Weight136.11
        Density1.89
        Melting Point250°C
        TSCAYes
        Solubility难溶
        Appearance powder
        Boiling Point533.4°C at 760 mmHg

        *以上化合物性质及应用等信息仅供参考