1,6-Diaminohexane 1,6-二氨基己烷

规格: 99%
CAS: 124-09-4
产品编号: H74452
MDL: MFCD00008243
品牌: INFI
Chemical Name1,6-Diaminohexane
Synonym 1,6-Hexanediamine {LY} 1,6-Hexanediamine 1,6-Hexanediamine, 98+% 1,6-Hexanediamine,~99% 1,6-Hexylenediamime 1,6-Hexylenediamine 1,6-diamino-hexan 1,6-diaminohexamethylene 1,6-diaminohexane 1,6-diaminohexane dihydrochloride 1,6-diaminohexane dihydrochloride, 1-(11)C-labeled 1,6-diaminohexane dihydrofluoride 1,6-diaminohexane monohydrochloride 1,6-hexamethylenediamine 1,6-hexane diamine 1,6-hexanediamine NSC 9257 {} {LY} 1,6-Hexanediamine {} {} {LY} 1,6-Hexanediamine {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {} {} {} {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {} {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {} {} {} {} {} {LY} 1,6-Hexanediamine {} {} {} {} {} {}
CAS Number124-09-4
PubChem Substance ID16402
EC Number204-679-6
Beilstein Registry Number4,269
MDL NumberMFCD00008243
Reaxys-RN1098307
Merck Number4695
Chemical Name Translation1,6-己烷二胺
Wiswesser Line NotationZ6Z
LabNetwork Molecule IDLN00193766
InChIInChI=1S/C6H16N2/c7-5-3-1-2-4-6-8/h1-8H2
Canonical SMILESNCCCCCCN
GHS Symbol
{haz

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,74,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/y

TYPE OF TEST            : LC - Lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >950 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-1090-0979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#02313

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 66500 mg/kg
SEX/DURATION            : multigeneration
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   16,490,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - hepatobiliary system
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 7,259,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 77 gm/kg
SEX/DURATION            : multigeneration
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   16,490,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 414 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotox

WGK Germany1
Hazard Codes C
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H302+H312
  • H312 Harmful in contact with skin 皮肤接触有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
    Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
    RTECSMO1180000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P301+P312
    • P301+P312+P330
    • P301+P330+P331
    • P301+P330+P331+P310
    • P302+P352
    • P303+P361+
    • P303+P361+P353
    • P304+P340
    • P304+P340+P310
    • P305+
    • P305+P351+P338
    • P305+P351+P338+P310
    • P307+P311
    • P308+P311
    • P308+P313
    • P309+P311
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
    • P330 Rinse mouth. 漱口
    • P333+P313
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P403+P233
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      UN Number 2280
      Safety Statements
      • S22 Do not breathe dust 不要吸入粉尘；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
        Risk Statements
        • R34 Causes burns 会导致灼伤
        • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
        • R37 Irritating to respiratory system 刺激呼吸道
          Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
          Packing GroupIII
          Hazard Class8
          Warnings 危化品目录(2015) 危险化学品
        • 有机合成，尼龙66中间体。
        • {uni_hamburg} Short: III/20a
        • {ALD} Merck: 14,4695
        • {ALF} A method for conversion of primary amines to isocyanates avoiding the use of phosgene is illustrated by the reaction of this diamine with CO2 at atmospheric pressure in the presence of triethylamine. Subsequent dehydration of the intermediate carbamate anion with POCl3 gives the diisocyanate in 90% isolated yield: J. Chem. Soc., Chem. Commun., 957 (1994).
        • {ALD} Merck: 14,4695
        • Beilstein:4,269
        • {uni_hamburg} Short: III/5a
          • 124-09-4 H74452 1,6-Diaminohexane 1,6-二氨基己烷

          化学属性

          Mol. FormulaC6H16N2
          Mol. Weight116
          Refractive indexn20/D 1.439(lit.)
          Boiling Point205°C(lit.)
          Density0.89
          Melting Point40.0 to 44.0 deg-C
          Flash Point93.89°C
          TSCAYes
          Vapor Density4 (vs air)
          Solubility490 G/L (20 ºC)
          Stability对空气及湿度敏感

          *以上化合物性质及应用等信息仅供参考