2,3-Pyridinedicarboxylic Acid 2,3-吡啶二甲酸

规格: 98%
CAS: 89-00-9
产品编号: H73783
MDL: MFCD00006295
品牌: INFI
Chemical Name2,3-Pyridinedicarboxylic Acid
CAS Number89-00-9
Alfabeta NamePYRIDINEDICARBOXYLICACID 23--,
MDL NumberMFCD00006295
EC Number201-874-8
Beilstein Registry Number137110
Synonym 2,3-PYRIDINEDICARBOXYLIC ACID 2,3-PYRIDINEDICARBOXYLIC ACID (QUINOLINIC ACID) 2,3-Pyridinedicarboxylic 2,3-PyridinedicarboxylicAcid99% 2,3-二羧酸吡啶 2,3-吡啶二甲酸 2,3-吡啶二甲酸(2,3-吡啶二羧酸) 2,3-吡啶二甲酸;2,3-二羧酸吡啶;吡啶-2,3-二甲酸;喹啉酸 2,3-吡啶二羧酸 2,3-吡啶二羧酸 PYRIDINE-2,3-DICARBOXYLI ACID 3-二羧酸 AKOS BBS-00003814 PDC PYRIDINE-2,3-DICARBOXYLIC ACID Pyridin-2,3-dicarbonsaeure Pyridine-2,3-dicarboxylate Quinolinic acid QuinolinicAcid>99% RARECHEM AL BO 0810 吡啉酸 吡啶-2 吡啶-2,3-二甲酸 吡啶-2,3-二羧酸 吡啶-2,3-二酸 吡啶羧酸 喹啉酸
PubChem Substance ID1066
Merck Number8073
Chemical Name Translation2,3-吡啶二甲酸
Reaxys-RN137110
LabNetwork Molecule IDLN00009465
InChIInChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1050 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   ETPAEK Experimental and Toxicologic Pathology.  (Gustav Fischer Verlag Jena,
   Postfach 100537, D-07705 Jena, Germany)  V.44-    1992-
   Volume(issue)/page/year: 46,323,1994

Warnings IRRITANT
Signal word Warning
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37 Wear suitable gloves 戴适当手套；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P302+P352+P332+P313+P362+P364
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
          RTECSUS7967250
          Hazard Codes Xi
        • A matabolite of tryptophan and a putative NMDA receptor agonist.
        • {MCE} [2]. Jang S, et al. Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition. Brain Res. 2010 Feb 8;1313:25-33.
        • {ALD} Merck: 14,8073
        • {ALD} Merck: 14,8073
        • Beilstein:22,150
        • {MCE} [1]. Heyes MP, et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain. 1992 Oct;115 ( Pt 5):1249-73.
        • {MCE} [1]. Heyes MP, et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain. 1992 Oct;115 ( Pt 5):1249-73.
        • {MCE} [2]. Jang S, et al. Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition. Brain Res. 2010 Feb 8;1313:25-33.
          • 89-00-9 H73783 2,3-Pyridinedicarboxylic Acid 2,3-吡啶二甲酸

          化学属性

          Mol. FormulaC7H5NO4
          Mol. Weight167
          Melting Point188-190
          TSCAT
          Density1.422
          Appearance 无色柱状结晶。 微溶于水，不溶于苯和醚。
          SolubilitySoluble in water (partly), alkalies, dilute aqueous base, DMSO, and alcohol (slightly).

          *以上化合物性质及应用等信息仅供参考