2-Aminopyridine 2-氨基吡啶

规格: 99%
CAS: 504-29-0
产品编号: H72475
MDL: MFCD00006312
品牌: INFI
Chemical Name2-Aminopyridine
CAS Number504-29-0
Alfabeta NameAMINOPYRIDINE 2-
MDL NumberMFCD00006312
Synonym 1,2-Dihydro-2-iminopyridine 2-AP 2-Aminopryidine 2-PYRIDINYLAMINE 2-Pyridinamine 2-aminopyridine 2-吡啶基胺 2-吡啶胺 2-吡啶胺;α-氨基氮杂苯;邻氨基吡啶;2-吡啶基胺;α-氨基吡啶;2-AP 2-氨基吡啶 2-氨基氮杂苯 2APY A-PYRIDYLAMINE AMINOPYRIDINE, 2- alpha-Pyridylamine alpha-aminopyridine alpha-aminopyridine, hydrochloride alpha-aminopyridine, mononitrate alpha-aminopyridine, sulfate o-Aminopyridine ortho-aminopyridine pyridin-2-ylamine α-氨基吡啶 邻氨基吡啶
PubChem Substance ID10439
EC Number207-988-4
Beilstein Registry Number105785
Reaxys-RN105785
Merck Number473
Chemical Name Translation2-氨基吡啶
Wiswesser Line NotationT6NJ BZ
LabNetwork Molecule IDLN00158377
InChIInChI=1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)
GHS Symbol
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE

{haz

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 211,367,1950

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,838,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Vo

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 226,163,1955

Warnings 危化品目录(2015) TOXIC
WGK Germany3
Hazard Codes 6.1 T T,Xi
Hazard statements
  • H301+H311
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
    Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
    RTECSUS1575000
    Precautionary statements
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P310
    • P301+P310+P330
    • P302+P350
    • P302+P352
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P307+P311
    • P308+P311
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
    • P330 Rinse mouth. 漱口
    • P332+P313
    • P337+P313
    • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Safety Statements
      • S20 When using do not eat or drink 使用时，不得进食，饮水；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时，佩带适当的呼吸器；
      • S4 Keep away from living quarters 远离生活区；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染；
      • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
      • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
        Risk Statements
        • R21 Harmful in contact with skin 与皮肤接触有害
        • R25 Toxic if swallowed 吞咽有毒
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
          UN Number 2671
          Storage condition 0-10 Hygroscopic 0-10°C 储存温度2-8℃,充氩保存
          Packing GroupII
          Hazard Class6.1
          Restrict 危险品
        • A compound has been shown to reversibly block voltage-dependent potassium channels.
        • {TRC} Williams, D.M., et al.: J. Biol. Chem., 275, 38127 (2000),
        • {uni_hamburg} Short: III/20a
        • {uni_hamburg} Short: II/6
        • {ALD} Merck: 14,473
        • {uni_hamburg} Short: EINECS
        • {ALD} Merck: 14,473
        • Beilstein:22(3/4)3840
          • 504-29-0 H72475 2-Aminopyridine 2-氨基吡啶

          化学属性

          Mol. FormulaC5
          Mol. Weight94
          Melting Point54-58
          Boiling Point204-210
          Density1.107
          Flash Point92°(197°F)
          TSCAYes
          Solubility略溶于水. 1-5 G/100 ML AT 19 ºC
          Stability对热、光、湿度敏感

          *以上化合物性质及应用等信息仅供参考