2-Aminobenzimidazole 2-氨基苯并咪唑

规格: 99%
CAS: 934-32-7
产品编号: H59527
MDL: MFCD00005596
品牌: INFI
Chemical Name2-Aminobenzimidazole
Synonym 2-Aminobenzimidazole {LY} 2-Aminobenzimidazole {} {LY} 2-Aminobenzimidazole {} {} {LY} 2-Aminobenzimidazole {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminobenzimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {
CAS Number934-32-7
PubChem Substance ID87562368
EC Number213-280-6
Beilstein Registry Number116525
MDL NumberMFCD00005596
Reaxys-RN116525
Alfabeta NameBENZIMIDAZOLAMINE H12---
Chemical Name Translation2-氨基苯并咪唑
Wiswesser Line NotationT56 BM DNJ CZ
LabNetwork Molecule IDLN00002280
Canonical SMILESNC1=NC2=CC=CC=C2N1
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,22,1953

TYPE OF TEST            : LD40 - Lethal Dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 67,905,1945

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 126 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29QHAQ "Principles of Medicinal Chemistry," Foye, W.O., et al., eds.,
   Philadelphia, Lea & Febiger, 1974  Volume(issue)/page/year: -,246,1974

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 15,273,1972

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2 mg/disc
REFERENCE :
   JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food
   Contaminants, and Agricultural Wastes.  (Marcel Dekker, 270 Madison Ave.,
   New York, NY 10016)  V.B11-    1976-  Volume(issue)/page/year: 21,319,1986

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 710 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 426 mg/kg
SEX/DURATION            : female 8-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 31,505,1976

WGK Germany3
Hazard Codes Xn
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H302+H312+H332
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
    RTECSDD5775000
    Precautionary statements
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P312
    • P301+P312+P330
    • P302+P350
    • P302+P352
    • P302+P352+P312+P362+P364
    • P304+P340+P312
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P332+P313
    • P337+P313
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Warning
      Safety Statements
      • S22 Do not breathe dust 不要吸入粉尘；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
        Risk Statements
        • R22 Harmful if swallowed 吞咽有害
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
        • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
          Warnings IRRITANT
          Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
        • 2-Aminobenzimidazole was used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles
        • {uni_hamburg} Short: EINECS
        • {uni_hamburg} Short: IV/8A
        • {ALF} For a review of the use of 2-aminobenzimidazoles in organic synthesis, see: Synthesis, 861 (1983).
        • {ALD} Beilstein:24,116
          • 934-32-7 H59527 2-Aminobenzimidazole 2-氨基苯并咪唑

          化学属性

          Mol. FormulaC7H7N3
          Mol. Weight133
          Melting Point226-230°C
          Density1.367
          TSCAYes
          Stability对光敏感
          SolubilitySoluble in water (Slightly).,
          Boiling Point235.67 °C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考