N-Methyl morpholine N-甲基吗啉

规格: 99.5%
CAS: 109-02-4
产品编号: H58993
MDL: MFCD00006175
品牌: INFI
Chemical NameN-Methylmorpholine
CAS Number109-02-4
EC Number203-640-0
Beilstein Registry Number102719
MDL NumberMFCD00006175
Synonym 4-METHYL-1-OXA-4-AZACYCLOHEXANE 4-METHYLMORPHOLINE 4-METHYLMORPHOLINE REAGENTPLUS(TM) 9& 4-METHYLMORPHOLINE, FOR PROTEIN SEQUENCE ANALYSIS 4-METHYLMORPHOLINE, REDISTILLED, 99.5+% 4-Methyl-1-oxa-4-azacyclohexane; N-Methylmorpholine 4-Methylmorf 4-Methylmorpholine 4-methyl-morpholin 4-methyl-morpholine 4-methyl-morpholinium 4-methylmorpholine 4-甲基吗啉 4-甲基吗啉; 4-甲基吗啡啉; N-甲基吗啡啉; 1,4-氧氮杂环庚烷 AKOS 89985 LUPRAGEN(R) N 105 Lupragen N 105 Lupragen® N 105 Methylmorpholine Morpholine,4-methyl- N-METHYLMORPHOLINE N-Methyl-morpholine N-Methylmorpholine N-甲基吗啡啉 NMM Texacat NMM p-Methyl morpholine
PubChem Substance ID7972
Merck Number6277
Chemical Name TranslationN-甲基吗啡啉
Reaxys-RN102719
Wiswesser Line NotationT6N DOTJ A1
LabNetwork Molecule IDLN00195500
InChIInChI=1S/C5H11NO/c1-6-2-4-7-5-3-6/h2-5H2,1H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1917 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 39(4),86,1974

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 31,60,1949

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25200 mg/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see T

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1960 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,85,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 perce

Signal word Danger
WGK Germany1
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
    • R22 Harmful if swallowed 吞咽有害
    • R34 Causes burns 会导致灼伤
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P211 Do not spray on an open flame or other ignition source.? 不要喷洒在明火或其他点火源。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P303+P361+P353
      • P304+P340
      • P305+P351+P338
      • P305+P351+P338+P310
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H302 Harmful if swallowed 吞食有害
        • H302+H312+H332
          Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          RTECSQE5775000
          Packing GroupII
          UN Number 2535 UN 2535 3/PG 2 UN2535
          Hazard Codes 3 F,C
          Storage condition Store at RT. 密封阴凉避光保存。
          Hazard Class3/8
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 萃取溶剂，催化剂，腐蚀抑制剂、分析试剂及药品制造等
        • {ALD} Merck:14,6277
        • {uni_hamburg} Short: III/20a
        • {uni_hamburg} Short: II/14a
        • {ALD} Merck:14,6277
        • Beilstein:27,6
        • {uni_hamburg} Short: III/35B
        • {ALF} Widely used base in peptide chemistry, milder than triethylamine. Recommended for the avoidance of racemization in the mixed anhydride method of coupling: J. Am. Chem. Soc., 88, 1338 (1966); 89, 5012 (1967). Also preferred in many cases for the formation of active esters or the neutralization of acid salts. For peptide reagents, see Appendix 6.
          • 109-02-4 H58993 N-Methyl morpholine N-甲基吗啉

          化学属性

          Mol. FormulaC5H11NO
          Mol. Weight101
          Density0.9081
          Refractive index1.4340 to 1.4370
          Vapor Density>;1 (vs air)
          Boiling Point115 - 116 °C/750 mmHg(lit.)
          Vapor Pressure18 mmHg ( 20 °C)
          Melting Point-66
          Flash Point57.2 °F
          TSCAYes
          Solubility与水混溶，溶于苯。
          Stability对光敏感
          pH:A

          *以上化合物性质及应用等信息仅供参考