1,4-Dicyanobutane 己二腈

规格: 98.5%
CAS: 111-69-3
产品编号: H53217
MDL: MFCD00001975
品牌: INFI
Chemical NameAdiponitrile
CAS Number111-69-3
EC Number203-896-3
Beilstein Registry Number1740005
MDL NumberMFCD00001975
Synonym 1，4-二氰基丁烷 1,4-DICYANOBUTANE ADN Adipic acid nitrile Adipinsäuredinitril Adiponitrile adipylnitrile 己二晴 己二腈
PubChem Substance ID87561850
Chemical Name Translation己二腈
Reaxys-RN1740005
Wiswesser Line NotationNC4CN
LabNetwork Molecule IDLN00199485
GHS Symbol
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1710 mg/m3/4H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Ear) - change in acuity
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 1,76,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 172 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   57,88,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MELAAD Medicina del Lavoro.  Industrial Medicine.  (Via S. Barnaba, 8, 20122
   Milan, Italy) V.16-    1925-  Volume(issue)/page/year: 46,221,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent -

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz.  (Darmstadt, Fed.
   Rep. Ger.)  V.1-25, 1951-75.  Volume(issue)/page/year: 19,225,1969

TYPE

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1120 mg/kg
SEX/DURATION            : female 6-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   7,33,1986

Signal word Danger
WGK Germany1
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
    Risk Statements
    • R20 Harmful by inhalation 吸入有害
    • R25 Toxic if swallowed 吞咽有毒
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
      • P301+P310
      • P301+P310+P330
      • P302+P352
      • P304+P340
      • P304+P340+P310
      • P304+P340+P312
      • P305+P351+P338
      • P308+P311
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P405 Store locked up. 上锁保管。
        RTECSAV2625000
        Hazard statements
        • H301 Toxic if swallowed 吞食有毒
        • H315 Causes skin irritation 会刺激皮肤
        • H330 Fatal if inhaled 吸入致命
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
        • H332 Harmful if inhaled 吸入有害
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Packing GroupIII
          UN Number 2205
          Hazard Codes 6.1 T
          Hazard Class6.1
          Storage condition 密封阴凉保存。
          Warnings 危化品目录(2015)
          Restrict 危险品
        • {uni_hamburg} Short: III/20a
        • {uni_hamburg} Short: IV/10A
        • {ALD} Beilstein:2(4)1975
        • {uni_hamburg} Short: III/38B
          • 111-69-3 H53217 1,4-Dicyanobutane 己二腈

          化学属性

          Mol. FormulaC6H8N2
          Mol. Weight108
          Density0.95
          Refractive index1.4370 to 1.4400
          Autoignition Point1022 °F
          Vapor Density3.7 (vs air)
          Boiling Point295
          Vapor Pressure0.01 mmHg ( 40 °C)
          Melting Point1-3
          Flash Point93°C(lit.)
          TSCAYes
          Solubility微溶于水、醚，溶于醇。

          *以上化合物性质及应用等信息仅供参考