tert-Butyl bromoacetate 溴乙酸叔丁酯

规格: 98%
CAS: 5292-43-3
产品编号: H52538
MDL: MFCD00000188
品牌: INFI
Chemical Nametert-Butyl bromoacetate
CAS Number5292-43-3
Alfabeta NameBUTYLBROMOACETATE TERT-
MDL NumberMFCD00000188
PubChem Substance ID87564388
EC Number226-133-6
Beilstein Registry Number1753010
Reaxys-RN1753010
Synonym 1-Butylbromoacetate 2-BROMOACETIC ACID-TERT-BUTYL ESTER 2-Bromoacetic acid-t-butylester tert-Butylbromacetat Acetic acid, bromo-, tert-butyl ester BUTYLBROMOACETATE-TERT Bromessigsäure-tert-butylester Bromoacetic acid tert-butyl ester T-BUTYL 2-BROMOACETATE T-BUTYL BROMOACETATE TERT-BUTYL BROMOACETATE aceticacid,bromo-,1,1-dimethylethylester bromoacetic acid tert-butyl ester bromoacetic acid T-butyl ester t-butyl bromoacetate tert-Butyl bromoacetate, 99 % tert-Butylbromoacetate,98%
Chemical Name Translation溴乙酸叔丁酯
InChIKeyBNWCETAHAJSBFG-UHFFFAOYSA-N
LabNetwork Molecule IDLN00223773
InChIInChI=1S/C6H11BrO2/c1-6(2,3)9-5(8)4-7/h4H2,1-3H3
GHS Symbol
Warnings IRRITANT-HARMFUL, LACHRYMATOR, FLAMMABLE 危化品目录(2015)
WGK Germany3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    Hazard Codes 3
    Precautionary statements
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241+P242+P243
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P330+P331+P310
    • P303+P361+P353
    • P303+P361+P353+P310+P363
    • P304+P340+P310
    • P305+P351+P338
    • P305+P351+P338+P310
    • P403+P235
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Warning
      Safety Statements
      • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
      • S20 When using do not eat or drink 使用时，不得进食，饮水；
      • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
      • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
        Risk Statements
        • R10 Flammable 易燃
        • R22 Harmful if swallowed 吞咽有害
        • R34 Causes burns 会导致灼伤
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
          UN Number 1993 2924 UN2924
          Packing GroupIII
          Hazard Class3/8
          Storage condition 0-6°C
          Restrict 危险品
        • 常规烷基化试剂，用于合成胶原酶抑制剂(S,S,R)-(-)-actinonin；乙酸叔丁酯中间体等等。
        • {ALFA} In the Reformatsky synthesis of ß-hydroxy acids, competing ß-elimination and retro-aldol type cleavage are minimized by the use of the t-butyl ester, and heating the reaction mixture in dry benzene leads directly to the hydroxy acid, avoiding the need for a separate hydrolysis step: Chem. Commun., 679 (1969); J. Chem. Soc. (C), 2799 (1969). For a review of advances in the Reformatsky reaction, see: Synthesis, 571 (1989). Addition of the same organozinc reagent to nitriles gives amino acrylates, which can be hydrolyzed to ß-keto-esters (Blaise reaction). For extension of this reaction to hindered nitriles, see: J. Org. Chem., 48, 3833 (1983).
        • {ALD} Beilstein:2(3)482
        • {uni_hamburg} Short: III/35E
        • {SA} 3. Angew. Chem. Int. Ed. Engl. 45 , 6349, (2006)
          • 5292-43-3 H52538 tert-Butyl bromoacetate 溴乙酸叔丁酯

          化学属性

          Mol. FormulaC6H11BrO2
          Mol. Weight195.0
          Boiling Point50
          TSCAT
          Refractive index1.4440 to 1.4460
          Density1.301
          Flash Point49 °C - 闭杯
          Solubility不溶于水，溶于乙醇、乙醚等多数有机溶剂。
          Stability催泪
          Melting Point50 °C 在 10 mmHg - lit.

          *以上化合物性质及应用等信息仅供参考