2-Thiazoline-2-thiol 2-巯基噻唑啉

规格: 99%
CAS: 96-53-7
产品编号: H50775
MDL: MFCD00126013
品牌: INFI
Chemical Name2-Thiazoline-2-Thiol
CAS Number96-53-7
Synonym 2-Mercapto-2-thiazoline {LY} 2-Mercapto-2-thiazoline {} {LY} 2-Mercapto-2-thiazoline {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mercapto-2-thiazoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
MDL NumberMFCD00126013
EC Number202-512-1
Beilstein Registry Number106332
PubChem Substance ID87572178
Reaxys-RN106332
Chemical Name Translation2-巯基噻唑啉
InChIKeyWGJCBBASTRWVJL-UHFFFAOYSA-N
LabNetwork Molecule IDLN00220548
InChIInChI=1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
Canonical SMILESS=C1SCCN1
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 97,478,1949

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 90,260,1947

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 14,111,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RAREAE Radiation Research.  (Academic Press, Inc., 1 E. First St., Duluth,
   MN 55802)  V.1-    1954-  Volume(issue)/page/year: 7,22,1957

Signal word Danger
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
    Risk Statements
    • R22 Harmful if swallowed 吞咽有害
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
      • P301+P310
      • P301+P310+P330
      • P305+P351+P338
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H301 Toxic if swallowed 吞食有毒
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
          RTECSXJ6122000
          Packing GroupIII
          UN Number 2811 UN 2811 6.1/PG 3
          Hazard Codes 6.1 Xn
          Hazard Class6.1
          Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
        • 用于高选择性手性合成青霉烷和碳青霉烷类 β-内酰胺抗生素的工具。
        • {ALF}
        • {ALF} Reaction with ɑ-bromo esters gives the S-alkoxycarbonylmethyl derivatives, which can be C-alkylated by alkyl halides, using NaH as base. Sulfur-free products can be obtained by reduction (Zn/AcOH) to give the substituted acetic acid, or by reaction with iodidomethane to give the corresponding ɑ-iodo ester: Tetrahedron Lett., 2677 (1977).
        • {TRC} Thomes, J. et al.: Jap. J. Pharmacol., 58, 201 (1992); Buxeraud, J. et al.: Eur. J. Med. Chem., 20, 43 (1985); Cheng, J. et al.: Nongyao, 38, 12 (1999);
        • {ALF} Used in the chain-lengthening of alkyl halides by trans-iodopropenylenation: Org. Synth. Coll., 6, 704 (1988):
          • 96-53-7 H50775 2-Thiazoline-2-thiol 2-巯基噻唑啉

          化学属性

          Mol. FormulaC3H5NS2
          Mol. Weight119.21
          Density1.422
          Melting Point100-105°C
          TSCAYes
          Solubility溶于热水
          Boiling Point188.9°C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考