Benzotrichloride 三氯化苄

规格: 98%
CAS: 98-07-7
产品编号: H45450
MDL: MFCD00000786
品牌: INFI
Chemical Nameα,α,α-Trichlorotoluene
MDL NumberMFCD00000786
CAS Number98-07-7
Synonym Benzylidyne chloride 苄基三氯 benzenyltrichloride ( omega,omega,omega-Trichlorotoluene BENZYLTRICHLORIDE α Benzen trichloromethyl-benzene (trichloromethyl)-benzen Benzene,(trichloromethyl)- ω,ω,ω-三氯甲苯 (Trichlormethyl)-benzol Toluene trichloride (trichlormethyl)benzene Trichlormethylbenzol RCRA waste number U023 benzenylchloride 三氯甲苯 1-(trichloromethyl) (trichloromethyl)benzene benzotrichloride Phenyltrichloromethane {uni_hamburg Benzenyl trichloride ω,ω, ω-Trichlorotoluene alpha,alpha,alpha-Trichlorotoluene α,α,α-trichlorotoluene Chlorure de benzenyle {Che
Beilstein Registry Number5,300
PubChem Substance ID87576355
EC Number202-634-5
Merck Number1109
Chemical Name Translation三氯化苄
Reaxys-RN508152
Wiswesser Line NotationGXGGR
LabNetwork Molecule IDLN00221982
InChIInChI=1S/C7H5Cl3/c8-7(9,10)6-4-2-1-3-5-6/h1-5H
GHS Symbol
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1620 ppb/30M/22W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   SAIGBL Sangyo Igaku.  Japanese Journal of Industrial Health.  (Nippon Sangyo
   Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160,
   Japan)  V.1-    1959-  Volume(issue)/page/year: 28,352,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9200 mg/kg/50W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appe

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16320 mg/kg/31W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   72,655,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1380 mg/kg/25W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   INHEAO Industrial Health.  (National Institute of Industrial Health, 6-21-1
   Nagao, Tama-ku, Kawasaki, 213 Japan)  V.1-    1963- Volume(issue)/page/year:
   31,127,1993

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Liver - other changes
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: FYI-OTS-1180-0107

TYPE OF TEST            : LC50 - Lethal concen

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 19 ppm/2H
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 29,73,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects no

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 60 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 2600 nmol/disc
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,143,1978

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 100 ug/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 27,94,1986

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 nmol/plate/20M
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,143,1978

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 ppm/6H/4W (Intermittent)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 164,272,1986

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 500 nmol/plate/20M
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE

WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H331 Toxic if inhaled 吸入中毒
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H350 May cause cancer 可能致癌
  • H318 Causes serious eye damage 严重伤害眼睛
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSXT9275000
    Precautionary statements
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P332+P313
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
    • P302+P350
    • P337+P313
    • P308+P313
    • P302+P352+P332+P313+P362+P364
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
    • P305+P351+P338
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P304+P340+P310
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P305+P351+P338+P337+P313
    • P301+P310+P331+P330
    • P405 Store locked up. 上锁保管。
    • P403+P233
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
      Signal word
      Packing GroupII
      UN Number UN 2226 8/PG 2 UN2226 2226
      Risk Statements
      • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
      • R45 May cause cancer 可能致癌
      • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
      • R22 Harmful if swallowed 吞咽有害
      • R23 Toxic by inhalation 吸入有毒
        Safety Statements
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
          Storage condition Moisture Sensitive
          Hazard Codes T
          Hazard Class8
          Warnings 危险化学品
        • 有机合成中间体。制造苯甲酸;氯化苯甲酰;三苯基甲烷染料;蒽醌染料和喹啉染料等。以及用于生产紫外线吸收剂。还用作分析化学试剂。
        • {ALD} Merck: 14,1109
        • {
        • {uni_hamburg} Short: III/20b
        • {uni_hamburg} Short: II/5
        • {ALD} Merck: 14,1109
        • Beilstein:5,300
        • {uni_hamburg} Short: II/2
        • 98-07-7 H45450 Benzotrichloride
三氯化苄

          化学属性

          Mol. FormulaC7H5Cl3
          Mol. Weight195.47
          Refractive index1.5570 to 1.5590
          Autoignition Point411 °F
          Vapor Density6.77 (vs air)
          Boiling Point219 - 223°C 760 mmHg(lit.)
          Vapor Pressure0.2 mmHg ( 20 °C)
          Density1.36
          Melting Point−7.5 - −7 °C(lit.)
          Flash Point103°C(lit.)
          TSCAYes
          Solubility水解
          Stability对光、湿度和空气敏感

          *以上化合物性质及应用等信息仅供参考