2-Chloropropionic acid 2-氯丙酸

规格: 95%
CAS: 598-78-7
产品编号: H42606
MDL: MFCD00004224
品牌: INFI
Chemical Name2-Chloropropionic Acid
Synonym Propionic acid, 2-chloro- (±)-2-Chloropropionic acid (RS)-2-Chloropropionic acid (±)-2-Chloropropanoic acid Propio 2-氯代丙酸 1-Chlorpropionsäure 2-Chlorpropansäure 2-氯丙酸 (R,S)-2-Chloro-propionicacid (±)-α-Chloropropanoic acid alpha-chloro-propionicaci (±)-2-chloro-propionic acid 2-Chloropropionic acid alpha-Monochloropropionic acid Propanoic acid, 2-chloro- (R,S)-2-Chloro-propionic acid (±)-2-Chloropropionicacid,97% α-氯代初油酸 ALPHA-氯丙酸 (+/-)-2-CHLOROPROPIONIC ACID 2-chloropropionic ALPHA-CHLOROPROPIONIC ACID 2-chloro-propionicaci A-CHLOROPROPIONIC ACID alpha-Chloropropionic acid
MDL NumberMFCD00004224
CAS Number598-78-7
EC Number209-952-3
Beilstein Registry Number1720259
PubChem Substance ID87565429
Reaxys-RN773799
Chemical Name Translation2-氯丙酸
Wiswesser Line NotationQVYG1
LabNetwork Molecule IDLN00201969
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - hematuria
   Skin and Appendages - hair
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555355

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 126 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85INA8 "Documentation of the Threshold Limit Values and Biological Exposure
   Indices," 5th ed., Cincinnati, OH, American Conference of Governmental
   Industrial Hygienists, Inc., 1986  Volume(issue)/page/year: 5,136(89),1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - hematuria
   Skin and Appendages - hair
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555355

RTECSUE8575000
Packing GroupIII
UN Number UN2511
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R35 Causes severe burns 会导致严重灼伤
  • R22 Harmful if swallowed 吞咽有害
  • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
    Safety Statements
    • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
    • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
    • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
    • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
    • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
    • S36 Wear suitable protective clothing 穿戴适当的防护服；
      WGK Germany1
      Hazard statements
      • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
      • H302 Harmful if swallowed 吞食有害
        Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
        Precautionary statements
        • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
        • P303+P361+P353+P310+P363
        • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
        • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
        • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
        • P305+P351+P338
        • P501 Dispose of contents/container to..… 处理内容物/容器.....
        • P405 Store locked up. 上锁保管。
        • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
        • P308+P311
        • P303+P361+P353
        • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
        • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
        • P304+P340+P310
        • P304+P340+P311
        • P403+P233
        • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
        • P305+P351+P338+P310
          Signal word
          Hazard Codes C
          Hazard Class8
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 用于有机合成及作为除草剂的中间体。
        • {ALF} Condensation of the dilithio-derivative with carbonyl compounds gives ɑß-epoxycarboxylic acids (glycidic acids) which afford methyl ketones on decarboxylation, avoiding possible ester hydrolysis in the classical Darzens glycidic ester condensation (see Ethyl­ chloroacetate, A15554): J. Org. Chem., 47, 1205 (1982). An analogous reaction of the dianion with ɑß-unsaturated esters gives, stereoselectively, cyclopropane cis-dicarboxylic acids: Synthesis, 284 (1982):
        • {ALD} Beilstein:2,248
        • {uni_hamburg} Short: EINECS
        • {uni_hamburg} Short: III/35E
        • {uni_hamburg} Short: III/38B
          • 598-78-7 H42606 2-Chloropropionic acid 2-氯丙酸

          化学属性

          Mol. FormulaC3H5ClO2
          Mol. Weight109
          Density1.182
          Refractive index1.4320 to 1.4360
          Flash Point106°C(lit.)
          TSCAYes
          Boiling Point170-190
          Melting Point-14--12°C
          Vapor Pressure4 mmHg ( 20 °C)
          Solubility与水混溶，可混溶于乙醚、丙酮、苯、四氯化碳。

          *以上化合物性质及应用等信息仅供参考