Barbital sodium 巴比妥钠

规格: 98%
CAS: 144-02-5
产品编号: H41519
MDL: MFCD00036203
品牌: INFI
Chemical NameSodium Barbital
Synonym {uni_hamburg} VERONAL SODIUM SALT { Barbital Na 巴比妥 Barbital, sodium deriv. Veronal sodium Diethylbarbiturate monosodium Sodium Veronal Sodium 5,5-diethylbarbiturate BARBITAL SODIUM SALT BARBITONE SODIUM SALT Barbital soluble 5,5-DIETHYLBARBITURIC ACID SALT SODIUM SALT 巴比酮鈉 Sodium barbitone VERONAL SODIUM {Chemi 二乙基巴比妥酸钠 5,5-Diethylbarbitursäure-Natriumsalz Thyalone BARBITAL SODIUM {uni_ham Sodium malonylurea 2,4,6(1H,3H,5H)- 5,5-二乙基巴比土酸钠盐 2,4,6(1H,3H,5H)-P BARBITAL NA Nervoseton {uni Embinal BARBITONE SODIUM 5,5-Diethylbarbituric acid sodium salt Sodium diethylbarbiturate 4 5,5-diethyl-barbituricacisodiumsalt Barbitone, sodium deriv. SODIUM 5,5-DIETHYLBARBITURATE 巴比妥鈉 Barbituric acid, 5,5-diethyl-, sodium salt 2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-,monosodiumsalt(9CI) barbital sodium (INN) S Natrinal 佛罗拿 钠盐 SODIUM BARBITAL Natriumbarbitals 5,5-DIETHYLBARBITURIC ACID SODIUM SALT SODIUM DIETHYLBARBITURATE 5,5-Diethy 5,5-Diethylbarbituric acid sodium deriv. Sodium ethylbarbital 5,5-二乙基巴比土酸 钠盐 5,5-二乙基巴比土酸 钠盐 佛罗拿 钠盐 巴比妥 巴比妥钠 Barbitone sodium DIETHYLBARBITURIC ACID SODIUM SALT 2,4,6(1H,3H,5H)-Pyrimidin Soluble barbital Barbitalnatrium Natrium-5,5-diäthylbarbiturat
MDL NumberMFCD00036203
PubChem Substance ID23681217
Beilstein Registry Number3921202
CAS Number144-02-5
EC Number205-613-9
Chemical Name Translation巴比妥钠(第二类精神管制类药品，不能销售）
Merck Number13,965
Wiswesser Line NotationT6VMVMV FHJ F2 F2 &-NA-
InChIInChI=1S/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1
GHS Symbol
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 mg/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 10,183,1989

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 121 gm/kg/72W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 11,2149,1990

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 60,125,1937

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 60,125,1937

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 830 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   27,70,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 31,1,1927

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        :

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2400 mg/kg
SEX/DURATION            : female 8-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   CUSCAM Current Science.  (Current Science Assoc., Sadashivanagar P.O.,
   Bangalore 560 080, India) V.1-    1932-  Volume(issue)/page/year: 36,3,1967

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   SJDBA9 Soviet Journal Developmental Biology (English Translation).
   Translation of Ontogenez. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.1-    1970-  Volume(issue)/page/year: 10,574,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : In

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 690 mg/kg
SEX/DURATION            : female 1-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,1309,1969

WGK Germany3
Hazard statements
  • H302 Harmful if swallowed 吞食有害
    Hazard Codes Xn
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
    Signal word Warning
    RTECSCQ3850000
    Packing GroupIII
    Hazard Class6.1(b)
    UN Number 3288
    Safety Statements
    • S36 Wear suitable protective clothing 穿戴适当的防护服；
      Risk Statements
      • R22 Harmful if swallowed 吞咽有害
        Storage condition 密封保存。
        Restrict {} 精神药品 精麻类化学品
      • 血清蛋白电泳,肝功能测定,配制缓冲溶液,细菌培养。
      • {ALD} Merck: 14,962
      • Beilstein: 24,IV,1904
      • {ALD} Merck: 14,962
      • {uni_hamburg} Short: III/20a
      • {uni_hamburg} Short: III/5a
      • {uni_hamburg} Short: III/10a
      • {uni_hamburg} Short: IV/1b
        • 144-02-5 H41519 Barbital sodium 巴比妥钠

        化学属性

        Mol. FormulaC8H12N2O3.Na
        Mol. Weight207.21
        Stability对湿度敏感
        Density1.0

        *以上化合物性质及应用等信息仅供参考