p-Anisidine 对甲氧基苯胺

规格: 99%
CAS: 104-94-9
产品编号: H38928
MDL: MFCD00007864
品牌: INFI
Chemical Namep-Anisidine
MDL Number-
CAS Number104-94-9
EC Number203-254-2
Beilstein Registry Number471556
Synonym 4-Anisidine {PubChem} para-anisidine {} {PubChem} p-anisidine {} {} {PubChem} 4-methoxyaniline {} {} {} {PubChem} 4-anisidine monoacid conjugate {} {} {} {} {} {} {} {} {PubChem} 4-anisidine hydrochloride {} {} {} {} {} {PubChem} 4-anisidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} para-anisidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} p-anisidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} 4-methoxyaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID7732
Merck Number667
Reaxys-RN471556
Chemical Name Translation对甲氧基苯胺
Wiswesser Line NotationZR DO1
LabNetwork Molecule IDLN00195921
InChIInChI=1S/C7H9NO/c1-9-7-4-2-6(8)3-5-7/h2-5H,8H2,1H3
Canonical SMILESNC1=CC=C(OC)C=C1
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo
   Instituta.  (Leningrad, Russia) V.1-145, 1949-82.  Discontinued.
   Volume(issue)/page/year: 128,14,1979

TYPE OF TEST            : LD50 - Lethal

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AGGHAR Archiv fuer Gewerbepathologie und Gewerbehygiene.  (Berlin, Ger.)
   V.1-18, 1930-61.  For publisher information, see IAEHDW.
   Volume(issue)/page/year: 15,447,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 806 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 17,900,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2900 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
   Blood - normocytic anemia
   Blood - other changes
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-

{h

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 196 umol/L
REFERENCE :
   MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
   Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-  Volume(issue)/page/year: 3,193,1988

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 202 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 203,155,

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 392 umol/L
REFERENCE :
   MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
   Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-  Volume(issue)/page/year: 3,193,1988

TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - mouse Bacteria - Escherichia coli
DOSE/DURATION           : 780 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 272,161,1992

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 160 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5(Suppl
   1),3,1983

Signal word Danger
WGK Germany3
Safety Statements
  • S1/2 None 上锁保管并避免儿童触及；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
    Risk Statements
    • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
    • R33 Danger of cumulative effects 有累积作用的危险
    • R45 May cause cancer 可能致癌
    • R50 Very toxic to aquatic organisms 对水生生物极毒
      Precautionary statements
      • P201 Obtain special instructions before use. 使用前获取专门指示。
      • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
      • P203
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P264+P265
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
      • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
      • P301+P310
      • P301+P310+P330
      • P301+P312
      • P301+P316
      • P301+P317
      • P302+P317
      • P302+P350
      • P302+P352
      • P302+P352+P312+P361+P364
      • P304+P340
      • P304+P340+P311
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P307+P311
      • P308+P311
      • P308+P313
      • P308+P316
      • P309+P311
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
      • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
      • P316
      • P318
      • P319
      • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗（见本标签上的）。
      • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
      • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
      • P330 Rinse mouth. 漱口
      • P332+P313
      • P337+P313
      • P337+P317
      • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
      • P361+P364
      • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
      • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
      • P403+P233
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H300 Fatal if swallowed 吞食致命
        • H301 Toxic if swallowed 吞食有毒
        • H301+H311+H331
        • H310 Fatal in contact with skin 皮肤接触致命
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H330 Fatal if inhaled 吸入致命
        • H350 May cause cancer 可能致癌
        • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
        • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
        • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
          Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
          RTECSBZ5450000
          Packing GroupIII
          UN Number 2431/2811 2811 UN 2811 6.1/PG 3 UN2431
          Hazard Codes 6.1 T+,N T+,N,Xi
          Hazard Class6.1
          Storage condition RT, stored under argon {LY} RT, stored under argon {} {LY} RT, stored under argon {} {} {LY} RT, stored under argon {} {} {} {LY} RT, stored under argon {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, stored under argon {} {} {} {} {} {} {} {}
          Warnings 危化品目录(2015)
          Restrict 危险品
        • An aromatic compound used in the detection of aldehydes or ketones in oils.
        • {uni_hamburg} Short: II/27B
        • {ALD} Merck:14,667
        • {uni_hamburg} Short: II/5
        • {uni_hamburg} Short: III/20a
          • 104-94-9 H38928 p-Anisidine 对甲氧基苯胺

          化学属性

          Mol. FormulaC7H9NO
          Mol. Weight123
          Density1.06
          Autoignition Point959 °F
          Boiling Point240 - 243 °C(lit.)
          Melting Point54 - 56°C
          Flash Point122 °C
          TSCAYes
          Solubility微溶于水，溶于乙醇、乙醚、丙酮、苯等多数有机溶剂。
          Appearance crystalline
          Refractive index1.5559
          Stability对光敏感
          pH:A

          *以上化合物性质及应用等信息仅供参考