Methyl isothiocyanate 异硫氰酸甲酯

规格: 98%, SpcSeal
CAS: 556-61-6
产品编号: H13599
MDL: MFCD00004818
品牌: INFI
Chemical NameMethyl Isothiocyanate
Synonym (Methylimino)(thioxo)methane AKOS BBS-00004313 Biomet 33 CH3NCS Isothiocyanatomethane; Methyl mustard-oil; MTC Isothiocyanic Acid Methyl Ester Isothiocyanic acid, methyl ester Isotiocianato di metile METHYL ISOTHIOCYANATE METHYL MUSTARD-OIL MIT (pesticide) MITC MUSTARD OIL MeNCS Methyl mustard oil Methyl-isothiocyanat Methylisothiocyanat Morton EP-161E Trapex Trapex-40 Trapexide WN 12 ai3-28257 isothiocyanatedemethyle isothiocyanatomethane isothiocyanic acid, methyl ester methane, isothiocyanato- 异硫氰酸甲酯 甲基异硫氰酸盐 硫代异氰酸甲酯
MDL NumberMFCD00004818
CAS Number556-61-6
PubChem Substance ID125309560
EC Number209-132-5
Beilstein Registry Number605319
Merck Number6092
Chemical Name Translation异硫氰酸甲酯
Reaxys-RN605319
Wiswesser Line NotationSCN1
LabNetwork Molecule IDLN00163276
InChIInChI=1S/C2H3NS/c1-3-2-4/h1H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 82 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NNGADV Nippon Noyaku Gakkaishi.  Journal of the Pesticide Science Society of
   Japan.  (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170,
   Japan)  V.1-    1976-  Volume(issue)/page/year: 15,297,1990

TYPE OF TEST

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 54 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NNGADV Nippon Noyaku Gakkaishi.  Journal of the Pesticide Science Society of
   Japan.  (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170,
   Japan)  V.1-    1976-

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NNGADV Nippon Noyaku Gakkaishi.  Journal of the Pesticide Science Society of
   Japan.  (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170,
   Japan)  V.1-    1976-  Volume(issue)/page/year: 15,297,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/y

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 250 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   NNGADV Nippon Noyaku Gakkaishi.  Journal of the Pesticide Science Society of
   Japan.  (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170,
   Japan)  V.1-    1976-  Volume(issue)/page/year: 15,297,1990

WGK Germany3
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H310 Fatal in contact with skin 皮肤接触致命
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H330 Fatal if inhaled 吸入致命
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
    Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges dust mask type N95 (US), Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges
    RTECSPA9625000
    Precautionary statements
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
    • P301+P310
    • P301+P310+P330
    • P302+P350
    • P302+P352+P310+P361+P364
    • P304+P340+P310
    • P305+P351+P338+P337+P313
    • P308+P311
    • P337+P313
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403+P233
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Safety Statements
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
      • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时，佩带适当的呼吸器；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
      • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
        Packing GroupI
        UN Number 2477
        Risk Statements
        • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
        • R34 Causes burns 会导致灼伤
        • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
        • R50/53
          Storage condition Moisture Sensitive 储存温度 2-8°C 2-8°C
          Hazard Codes 6.1 T,N
          Hazard Class6.1/3
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 用于氨基酸测序分析
        • {ALF} Amino acids are converted by this reagent into 2-thionoimidazolidin-4-ones, useful in protein analysis: Tetrahedron, 26, 5479 (1970); Anal. Lett., 359 (1970).
        • {ALD} Merck:14,6092
        • Beilstein:4(4)248
        • {uni_hamburg} Short: II/19b
        • {uni_hamburg} Short: II/19c
        • {ALD} Merck:14,6092
        • {ALF} Reaction with thioamides, e.g. 2-Cyanothioacetamide, A15436 and sulfur leads to thiazoline-2-thiones: J. Prakt. Chem., 332, 223 (1990):
        • {ALF} For general reactions of isothiocyanates, see Appendix 3.
          • 556-61-6 H13599 Methyl isothiocyanate 异硫氰酸甲酯

          化学属性

          Mol. FormulaC2H3NS
          Mol. Weight73
          Boiling Point107.8°C at 760 mmHg
          Vapor Pressure21 mmHg ( 20 °C)
          Density1.049
          Melting Point30 - 36℃
          Flash Point32.2°C
          TSCAYes
          Solubility微溶于水，易溶于乙醇、乙醚。
          Stability对湿度敏感
          pH:A

          *以上化合物性质及应用等信息仅供参考