(R)-(+)-Limonene (R)-(+)-柠檬烯

规格: 95%
CAS: 5989-27-5
产品编号: H13008
MDL: MFCD00062991
品牌: INFI
Chemical Name(R)-(+)-Limonene
Synonym (R)-Limonene {LY} (R)-Limonene 1-methyl-4-(1-methylethenyl)cyclohexene 4 Mentha 1,8 diene 4-mentha-1,8-diene AISA 5203-L (+)limonene cyclohexene, 1-methyl-4-(1-methylethenyl)-, (4R)- d Limonene d-limonene dipentene limonene limonene, (+)- limonene, (+-)- limonene, (+-)-isomer limonene, (R)-isomer limonene, (S)-isomer {} {LY} (R)-Limonene {} {} {LY} (R)-Limonene {} {} {} {LY} (R)-Limonene {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {} {} {} {} {} {LY} (R)-Limonene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {PubChem} (R)-4-isopropenyl-1-methylcyclohexene {} {} {} {}
CAS Number5989-27-5
PubChem Substance ID440917
EC Number227-813-5
Beilstein Registry Number2204754
MDL Number-
Merck Number5493
Reaxys-RN2204754
Alfabeta NameISOPROPENYLMETHYLCYCLOHEXENE R441()----
Chemical Name Translation(R)-(+)-柠檬烯
Wiswesser Line NotationL6UTJ A1 DY1&U1 -R
LabNetwork Molecule IDLN00183846
InChIInChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1
Canonical SMILESCC1=CC[C@H](C(C)=C)CC1
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 gm/kg/39W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   35,771,1965

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 38625 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
   Reproductive - Tumorigenic effects - testicular tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-347,1990

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30200 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - respiratory depression
   Skin and Appendages - hair
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 9,387,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3170 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
REFERENCE :
   SIZSAR Sapporo Igaku Zasshi.  Sapporo Medical Journal.  (Sapporo Igaku
   Daigaku, Nishi-17-chome, Minami-1-jo, Chuo-ku, Sapporo 060, Japan)  V.3-

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   OYYAA2 Oyo Yakuri.  P

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 8,1439,1974

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 3250 mg/kg
SEX/DURATION            : female 6-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - physical
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,885,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 20083 mg/kg
SEX/DURATION            : female 9-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 14178 mg/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,863,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3546 mg/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Effects on Newborn - physical
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,863,1977

WGK Germany3
Hazard Codes 3 Xi,N Xi;N
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSGW6360000
    Precautionary statements
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
    • P241+P242+P243
    • P242 Use only non-sparking tools. 只能使用无火花工具。
    • P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P310
    • P301+P316
    • P302+P352
    • P302+P352+P333+P313+P362+P364
    • P303+P361+P353
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P331 Do NOT induce vomiting.. 不要催吐。
    • P332+P313
    • P332+P317
    • P333+P313
    • P333+P317
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
    • P362+P364
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P370+P378
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403+P235
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger Warning
      UN Number 2319
      Risk Statements
      • R10 Flammable 易燃
      • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      • R38 Irritating to skin 刺激皮肤
      • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
      • R50/53
      • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
        Safety Statements
        • S24 Avoid contact with skin 避免皮肤接触；
        • S37 Wear suitable gloves 戴适当手套；
        • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
        • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
          Packing GroupIII
          Warnings 危化品目录(2015) IRRITANT
          Hazard Class3
          Storage condition 2-8°C {LY} 2-8°C 4°C 4°C, Light sensitive, Light sensitive {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
          Restrict 危险品
        • Which activates UGT and hepatic GST.
        • {ALD} Merck:14,5493
        • Beilstein: 5,IV,438
        • {ALF} Chiral building block. Biodegradable solvent.
        • {ALD} Merck:14,5493
          • 5989-27-5 H13008 (R)-(+)-Limonene (R)-(+)-柠檬烯

          化学属性

          Mol. FormulaC10H16
          Mol. Weight136
          Refractive index1.4700 to 1.4730
          Boiling Point-
          Density0.842
          Flash Point48.33°C
          TSCAYes
          Melting Point-74
          Vapor Density4.7 (vs air)
          Vapor Pressure<;3 mmHg ( 14.4 °C)
          Stability不溶于水。
          SolubilitySoluble in ethanol, carbon tetrachloride, and glycerin (slightly). Insoluble in water (0.02 mg/ml at 25 °C), and propylene glycol.

          *以上化合物性质及应用等信息仅供参考