Chemical Name | 4-(Bromomethyl)phenylboronic acid |
CAS Number | 68162-47-0 |
Alfabeta Name | BROMOMETHYLPHENYLBORONICACID 4()- |
MDL Number | MFCD01318113 |
Synonym |
α-Bromo-p-tolueneboronic acid p-Boronobenzyl bromide
α-Bromo-p-tolueneboronic acid
4-Boronobenzyl bromide
p-Boronobenzyl bromide
α-Bromo-p-tolueneboronic acid
4-(溴甲基)苯硼酸 |
PubChem Substance ID | 24885493 |
Beilstein Registry Number | 3030979 |
Chemical Name Translation | 4-(溴甲基)苯硼酸 |
WGK Germany | 3 |
GHS Symbol
Precautionary statements | |
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312
- P302+P352
- P305+P351+P338
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Hazard statements | |
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
|
Hazard Codes |
Xn |
Personal Protective Equipment |
dust mask type N95 (US), Eyeshields, Gloves |
Signal word |
Warning |
Safety Statements | |
- S22 Do not breathe dust 不要吸入粉尘;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
|
UN Number |
UN3261 |
Risk Statements | |
- R22 Harmful if swallowed 吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
|
Packing Group | III |
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1. H. M. H. G. Albers, et al., , Structure-Based Design of Novel Boronic Acid-Based Inhibitors of Autotaxin J. Med. Chem. 54 , 4619-4626, (2011)
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2. D. E. Morrison, et al., , Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, x-ray diffraction, in vitro cytotoxicity, and cellular uptake J. Biol. Inorg. Chem. 15 , 1305-1318, (2010)
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3. S. Gamsey, et al., , The effect of boronic acid-positioning in an optical glucose-sensing ensemble Tetrahedron 62 , 6321-6331, (2006)
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Q. Peng, et al., , Enhanced gene transfection capability of polyethylenimine by incorporating boronic acid groups Chem. Commun. 46 , 5888-5890, (2010)
{ALF} Has been employed in the synthesis of para-substituted boronated stilbenes via the Wittig reaction: J. Am. Chem. Soc., 117, 8982 (1995), which were subsequently employed as highly selective fluorescent probes for glucose: J. Phys. Chem. A, 105, 6834 (2001).