2-Furoic acid 糠酸

规格: 98%
CAS: 88-14-2
产品编号: H10218
MDL: MFCD00003238
品牌: INFI
Chemical Name2-Furoic acid
MDL NumberMFCD00003238
CAS Number88-14-2
Synonym 2-Furoic acid {LY} 2-Furoic acid {} {LY} 2-Furoic acid {} {} {LY} 2-Furoic acid {} {} {} {LY} 2-Furoic acid {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Furoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID6919
EC Number201-803-0
Beilstein Registry Number110149
Reaxys-RN110149
Merck Number4307
Chemical Name Translation糠酸
Wiswesser Line NotationT5OJ BVQ
LabNetwork Molecule IDLN00008646
InChIInChI=1S/C5H4O3/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)
Canonical SMILESO=C(C1=CC=CO1)O
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHREEB Pharmaceutical Research.  (Thieme Inc., 381 Park Ave. S, New York, NY
   10016)  No.1-    1984-  Volume(issue)/page/year: 2,233,1985

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   1,15,1978

WGK Germany3
Hazard Codes C;Xi C Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
    RTECSLV1763000
    Precautionary statements
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P302+P350
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P332+P313
    • P337+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      Signal word Warning
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
        Risk Statements
        • R22 Harmful if swallowed 吞咽有害
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
        • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
          Packing GroupII
          Hazard Class8
          Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
        • 糠酸用于合成甲基呋喃，糠酰胺及糠酸酯和盐。
        • {MCE} [2]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan;326(1):15-23.
        • {ALF} Adducts formed by the Diels-Alder trapping of arynes lose CO2 to give 1-naphthols: Tetrahedron, 42, 155 (1986); 45, 6281 (1989):
        • {ALD} Merck: 14,4307
        • {ALD} Merck: 14,4307
        • Beilstein:18,272
        • {uni_hamburg} Short: II/27B
        • {uni_hamburg} Short: III/35C2
        • {MCE} [1]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199.
        • {MCE} [1]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199.
        • {MCE} [2]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan;326(1):15-23.
          • 88-14-2 H10218 2-Furoic acid 糠酸

          化学属性

          Mol. FormulaC5H4O3
          Mol. Weight112.08
          Boiling Point230-232°C at 760 mmHg
          Melting Point128-132°C
          Flash Point137°(278°F)
          TSCAYes
          Solubility36 G/L (20 ºC)
          Density1.324

          *以上化合物性质及应用等信息仅供参考